Faculty Profile: Anderson, Aileen

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Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Anderson, Aileen
Lab Contact:
Aileen Anderson
aja@uci.edu
(949) 824-6750
A ANATOMY
Department: SOM - Physical Medicine & Rehabilitation
845 Health Science Road, 2030 Sue & Bill Gross Hall.

Research Description

Dr. Anderson is an Associate Professor in Physical Medicine & Rehabilitation and Anatomy & Neurobiology, with 20 years of research experience focusing on the mechanisms and pathways of central nervous system degeneration and regeneration. She is a member of the Stem Cell Research Center, Reeve-Irvine Research Center, Institute for Memory Impairments and Neurological Disorders, and Center for Immunology at the University of California at Irvine. In addition to her laboratory at UCI, she is the Director of the Christopher and Dana Reeve Paralysis Foundation (CDRF) Spinal Cord Injury (SCI) Research Core Facility, and a part of the CDRF International Consortium on Spinal Cord Injury. The CDRF SCI Core was established in 2001 as the first foundation-funded initiative of its kind, with the goal of enabling interdisciplinary and cross-institutional access to SCI animal models and training as an integral part of multiple CDRF research initiatives. Dr. Anderson's own research is focused on two principal goals. First, investigating the interactions of transplanted stem cell populations within the injured niche, including the role of the evolving inflammatory microenvironment in stem cell fate and migration decisions. Second, investigating the role of inflammatory mechanisms in degeneration and regeneration in the injured CNS, particularly the role of the innate immune response and complement pathways in these conflicting but intertwined processes. Much of the research in Dr. Anderson's laboratory bridges the junction between seeking to understand mechanism at the basic neuroscience level, and identifying translational neuroscience strategies to ameliorate the cellular and histopathological deficits associated with SCI to promote recovery of function.

Requirements to Participate

Attendance of Lab Meetings at least 1 qtr per year Completion of assigned lab safety training. On the last day of instruction of both the fall and winter quarter, students are required to turn in a 1-2 page summary of work completed. This can include background information obtained by reading the literature, details about a technique learned, and/or data generated. At the end of spring quarter, this paper will be replaced with a 15-minute scientific talk presented to the lab. All 199s are required to attend these talks.

Time Commitment per Week

12 hrs/wk

Faculty Means of Evaluation

Quality of work and data collection, proper use of lab equipment, following appropriate lab and university-mandated safety protocols, initiative and overall enthusiasm for research.