Faculty Profile: Hertel, Klemens

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Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Hertel, Klemens
Lab Contact:
Klemens Hertel
khertel@uci.edu
(949) 824-2127
A RNA SPLICING
Department: SOM - Microbiology & Molecular Genetics
Medical Sciences I

Research Description

Among several proposed mechanisms, alternative pre-mRNA splicing is considered to be one of the most efficient and widespread avenues to generate multiple protein isoforms from individual genes. Research in the Hertel lab uses experimental and computational approaches to elucidate the mechanisms of splice site selection with the long-term goal to faithfully predict alternative splicing changes in disease models. This knowledge will be used to devise strategies to correct defective pre-mRNA splicing. More detailed information can be found here: https://faculty.sites.uci.edu/hertellab/.

Requirements to Participate

1 year Commitment. 10 hours per week; knowledge of molecular biology and/or basic computer science.

Faculty Means of Evaluation

Performance in laboratory, effort and dedication to research, quarterly presentation on research progress.