Faculty Profile: Kiser, Philip

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Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Kiser, Philip
Lab Contact:
Philip Kiser
pkiser@uci.edu
949-824-6954
A CHEM BIO OF VISION
Department: Physiology and Biophysics
Gillespie Neuroscience Research Facility

Research Description

My laboratory studies the enzymes, transporters and binding proteins that constitute a metabolic pathway known as the visual cycle as well as a variety of other proteins important for the health of the retina. We use an array of experimental techniques and methodologies, including X-ray crystallography, electron microscopy, knockout mouse models, and classic biochemistry approaches to answer important questions about the structure and function of these proteins. Major emphasis is placed on the use of such information to develop effective therapeutics for currently untreatable retinal diseases.

Requirements to Participate

A good work ethic and scientific curiosity are the most important prerequisites. The ideal student will have background knowledge of biology, molecular biology, biochemistry and physiology and be proficient in carrying out basic laboratory calculations. Research projects may involve handling of experimental animals or animal tissues, so the student should not be intrinsically averse to such activities. 1 year Commitment.

Faculty Means of Evaluation

Attendance: 20Pts (working assigned hours, being on time)
Lab Work: 40Pts (quality, accuracy, integrated.synthesis of information and safety)
Communication: 20Pts (Written/Oral reports, questions and discussion with mentor)
Lab citizenship: 20Pts (organization, clean up and follow through)
Total: 100 points