Faculty Profile: Chen, Phang-Leng

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Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Chen, Phang-Leng
Lab Contact:
Phang-Leng Chen.
plchen@uci.edu
(949) 824-4008
A DNA DAMAGE RESPONSE
Department: SOM - Biological Chemistry
Med Sci 1, Room D268

Research Description

The central theme of my research is to elucidate the fundamental mechanisms governing genome integrity with specific emphasis on the intracellular signaling pathways involved in the DNA damage response and repair. Currently we focus on dissecting DNA surveillance mechanisms. Diverse molecular and genetic approaches using mammalian cell culture and yeast are being applied to delineate the DNA checkpoint factors in cell function; their role in DNA damage responses and repair

Requirements to Participate

COURSE COMPLETION: Cell Biology, Genetics, Molecular Biology, Biochemistry.

Time Commitment per Week

12 hrs/week

Faculty Means of Evaluation

Students will be graded based on their performance and given a numeric number of A through F.