Faculty Profile: Benmohamed, Lbachir

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Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Benmohamed, Lbachir
Lab Contact:
Lbachir Benmohamed
lbenmoha@uci.edu
(949) 824-8937
A OPHTHALMOLOGY
Department: SOM - Ophthalmology
Hewitt Hall, Building 843, 2nd Floor

Research Description

Immunology of Herpes Simplex Virus (HSV) Type 1 Latency and Pathogenesis The aim of this study is listed in three sections: 1) To develop a clinically acceptable vaccine strategy to reduce or eliminate ocular and genital herpes infection including recurrent disease. 2) Eventually, the candidate vaccines developed in mice will be tested in rabbits and humans. Techniques used in this project: Immunology, virology, and molecular biology - techniques that include vaccine studies in animal models. 3) To investigate if (1) LAT is involved in dendritic cells (DC) modulation (2) HSV-1 interferes with the migratory activity of DC in vivo (trafficking or homing), (3) LAT also plays a role in this viral activity. Development of immunotherapeutic and immunoprophylactic strategies against various cancers 1) The aim of this study is to develop a clinically acceptable Glyco lipopeptide vaccines to reduce or eliminate tumor cells 2) The candidate vaccines developed will be tested in mouse model of cancers. Techniques used in this project: Immunology, virology, and molecular biology - techniques that include vaccine studies in animal models.

Requirements to Participate

General background in biology/biochemistry/immunology/virology, oncology and/or infectious diseases. Strong motivation, good organizational skills, quick study and receptive to taking work direction. COURSE COMPLETION: Completion of core through Bio 99 with a grade of B or higher, completion of Bio 194S Safety, consent of instructor.

Time Commitment per Week

20 hrs/wk