Faculty Profile: Shi, Youngsheng

Return to Faculty Sponsors

Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Shi, Youngsheng
Lab Contact:
Youngsheng Shi
yongshes@uci.edu
(949) 824-0397
A MICROBIOL & MOL GEN
Department: SOM - Microbiology & Molecular Genetics
C135C, Medical Sciences I.

Research Description

All eukaryotic mRNA precursors must go through multiple RNA processing steps in the nucleus, including capping, splicing, and 3?-end processing, before being exported to the cytoplasm as mature mRNAs. These mRNA processing steps plays critical roles in post-transcriptional gene regulation. Additionally, alternative mRNA processing is a major mechanism for expanding protein diversity in metazoans. However, the molecular mechanism and regulation of mRNA processing remain poorly understood. The research project will focus on elucidate the fundamental mechanisms mRNA 3? processing of our lab is mRNA 3? end processing (cleavage/polyadenylation) by using a combination of genomic, proteomic, biochemical, and bioinformatic approaches

Requirements to Participate

COURSE COMPLETION: Biochemistry

Time Commitment per Week

10

Faculty Means of Evaluation

Research progress, dedication, and effort.