Faculty Profile: Laferla, Frank

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Faculty Information Lab Information (Packet Type, Course Title, & Department) Location
Laferla, Frank
Lab Contact:
Frank Laferla
A MOLEC NEUROPATH
Department: Neurobiology & Behavior
Laferla, Frank
Lab Contact:
Shirley Sirivong
leyley@uci.edu
(949) 824-8135
B ALZHEIMER'S DISEASE
Department: Neurobiology and Behavior
1100 Gottschalk Medical Plaza

Research Description

The UCI Alzheimer’s Disease Research Center (ADRC) was officially established in 2000 and is one of several multi-disciplinary and multi-investigator grants administered by the Institute for Memory Impairments and Neurological Disorders.
The mission of the UCI ADRC is to encourage multidisciplinary basic, clinical, and behavioral research in Alzheimer’s disease and translate findings into practice. As part of this mission, the ADRC trains scientists and health care providers who are new to Alzheimer’s disease research and provides education about Alzheimer’s disease and the related dementias throughout the community.
As Orange County’s only federally funded Alzheimer’s disease center, UCI ADRC seeks to translate research advances into improved diagnosis, treatment, and care for people living with mild cognitive impairment (MCI) Alzheimer’s disease or another dementia today and ultimately find a way to cure and possibly prevent these conditions. Our goals are to:
• Describe the cognitive and underlying brain changes that differentiate normal aging, Mild Cognitive Impairment (MCI), and Alzheimer’s disease
• Investigate ways to identify, diagnose, and treat Alzheimer’s disease and related disorders
• Better understand cognitive aging in special populations, including the oldest old and persons with Down syndrome
• Engage older adults in a variety of studies on memory and aging
• Serve as the expert source of information on memory and aging for Orange County seniors, health care professionals, and aging service providers, as well as the community at large.
Students interested in this clinical research opportunity will be engaged in human subject research within the UCI ADRC. Students will gain experience in the process of collecting patient information in clinical studies and with this direct patient interaction.

Requirements to Participate

Genuine interest in entering the medical or clinical research field. Interest in working with older adult population.

Time Commitment per Week

Minimum 8-10 hrs/wk, and willing to commit to at least 1-2 years

Faculty Means of Evaluation

Attendance, participation, data collection, professionalism, and quality of work.
Laferla, Frank
Lab Contact:
Malcolm Leissring
m.leissring@uci.edu
(904) 254-3050
A NEUROBIOLOGY
Department: Neurobiology and Behavior
3400A Biological Sciences III

Research Description

Our laboratory is focused on elucidating the molecular pathogenesis of Alzheimer's disease and also developing novel protein nanocapsules for drug delivery.

Requirements to Participate

Genuine interest in biomedical research. Competence performing mathematical calculations. Comfortable working with mouse models of disease.

Time Commitment per Week

Minimum 8-10 hrs/wk, and willing to commit to at least 1-2 years

What does it take to complete this course?

Attendance, participation, data collection, professionalism, and quality of work.

Faculty Means of Evaluation

Attendance: 20Pts (working assigned hours, being on time)
Lab Work: 40Pts (quality, accuracy, integrated.synthesis of information and safety)
Communication: 20Pts (Written/Oral reports, questions and discussion with mentor)
Lab citizenship: 20Pts (organization, clean up and follow through)
Total: 100 points